Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing-Reference-Cited by-同舟云学术

Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

Published:2016 Issue:51 Volume:52 Page:7935-7938
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Annoni Chiara¹²³⁴,Endoh Tamaki¹²³⁴,Hnedzko Dziyana⁵⁶⁷⁸⁹,Rozners Eriks⁵⁶⁷⁸⁹,Sugimoto Naoki¹²³⁴¹⁰

Affiliation:

1. Frontier Institute for Biomolecular Engineering Research (FIBER)

2. Konan University

3. Kobe 650-0047

4. Japan

5. Department of Chemistry

6. Binghamton University

7. State University of New York

8. Binghamton

9. USA

10. Faculty of Frontiers of Innovative Research in Science and Technology (FIRST)

Abstract

Extremely sensitive detection tool for single nucleobase editing from adenosine to inosine is reported using triplex-forming peptide nucleic acid.

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science, and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC02164F

Reference39 articles.

1. B. L. Bass , in The RNA World, ed. R. F. Gesteland, Cold Spring Harbor Lab. Press, NY, 1993, vol. 24, p. 383

2. FUNCTIONS AND MECHANISMS OF RNA EDITING

3. C-to-U RNA Editing: Mechanisms Leading to Genetic Diversity

4. RNA Editing by Adenosine Deaminases That Act on RNA

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