Electrochemical chemoselective hydroxyl group transformation: anthranilic acyl modification of tyrosine bioconjugations-Reference-Cited by-同舟云学术

Electrochemical chemoselective hydroxyl group transformation: anthranilic acyl modification of tyrosine bioconjugations

Published:2023 Issue:18 Volume:10 Page:4606-4615
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

You Shiqi¹^ORCID,Wang Ruitao¹,Ma Chao¹^ORCID,Lu Cuifen¹^ORCID,Yang Guichun¹,Liu Li¹^ORCID,Weng Yue¹,Gao Meng¹^ORCID

Affiliation:

1. Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China

Abstract

We report an electrochemically promoted transformation for accessing tyrosine-containing biomolecules with anthranilic acid derivatives. Utilizing TBAF as the hydrogen-bonding additive, the tyrosine residue can be well labelled under mild conditions.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00983A

Reference59 articles.

1. Chemoselectivity and the Curious Reactivity Preferences of Functional Groups

2. Chemoselectivity: The Mother of Invention in Total Synthesis

3. Chemoselectivity in Chemical Biology: Acyl Transfer Reactions with Sulfur and Selenium