Photophysical and biological assessment of coumarin-6 loaded polymeric nanoparticles as a cancer imaging agent-Reference-Cited by-同舟云学术

Photophysical and biological assessment of coumarin-6 loaded polymeric nanoparticles as a cancer imaging agent

Published:2023 Issue:5 Volume:2 Page:1277-1285
ISSN:2635-0998
Container-title:Sensors & Diagnostics
language:en
Short-container-title:Sens. Diagn.

Author:

Gregoriou Yiota¹²^ORCID,Gregoriou Gregoria²,Manoli Andreas³⁴,Papageorgis Paris³⁴,Mc Larney Benedict⁵^ORCID,Vangeli Despoina⁶,McColman Sarah⁷^ORCID,Yilmaz Vural²^ORCID,Hsu Hsiao-ting¹,Skubal Magdalena⁵,Ogirala Anuja¹,Athanasiou Evangelia³⁸^ORCID,Cramb David T.⁷^ORCID,Dietis Nikolas⁶,Strati Katerina²^ORCID,Itskos Grigorios³⁴,Constantinou Andreas I.²,Andreou Chrysafis³⁸^ORCID

Affiliation:

1. Memorial Sloan Kettering Cancer Center, New York, NY, USA

2. Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus

3. Emphasis Research Centre, University of Cyprus, Nicosia, Cyprus

4. Department of Physics, University of Cyprus, Nicosia, Cyprus

5. Molecular Pharmacology Program, Memorial Sloan Kettering, New York, NY, USA

6. Medical School, University of Cyprus, Nicosia, Cyprus

7. Department of Chemistry and Biology, Toronto Metropolitan (Ryerson) University, Toronto, ON, Canada

8. Department of Electrical and Computer Engineering, University of Cyprus, Nicosia, Cyprus

Abstract

Coumarin-6 is used as a model hydrophobic drug to investigate delivery to tumors via polymeric micelles. Photophysical characterization, as well as in vitro and in vivo experiments showcase this platform for cancer diagnosis and imaging.

Funder

Research and Innovation Foundation

Center for Strategic Scientific Initiatives, National Cancer Institute

Fulbright Association

Natural Sciences and Engineering Research Council of Canada

Toronto Metropolitan University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SD/D3SD00065F

Reference37 articles.

1. Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance