QSPR model for Caco-2 cell permeability prediction using a combination of HQPSO and dual-RBF neural network
Author:
Affiliation:
1. School of Chemical Engineering
2. University of Science and Technology Liaoning
3. Anshan 114051
4. China
5. School of Electronic and Information Engineering
Abstract
The aim of this study is to establish a promising QSPR model for the Caco-2 permeability prediction.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA08209K
Reference58 articles.
1. ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness
2. The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery
3. ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting
4. A fast screening model for drug permeability assessment based on native small intestinal extracellular matrix
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