ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting-Reference-Cited by-同舟云学术

ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting

Published:2016-04-05 Issue:4 Volume:56 Page:763-773
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Wang Ning-Ning¹,Dong Jie¹,Deng Yin-Hua¹,Zhu Min-Feng²,Wen Ming³,Yao Zhi-Jiang¹³,Lu Ai-Ping⁴,Wang Jian-Bing³,Cao Dong-Sheng¹⁴

Affiliation:

1. School of Pharmaceutical Sciences, Central South University, Changsha 410013, P. R. China

2. School of Mathematics and Statistics, Central South University, Changsha 410083, P. R. China

3. College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China

4. Institute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, P. R. China

Funder

Central South University

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.5b00642

Reference82 articles.

1. The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery

2. Strategies for Absorption Screening in Drug Discovery and Development

3. PAMPA—critical factors for better predictions of absorption

Cited by 154 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy;European Journal of Medicinal Chemistry;2024-10

2. Preclinical tests for salicylhydrazones derivatives to explore their potential for new antituberculosis agents;Tuberculosis;2024-09

3. In silico and ADMET molecular analysis targeted to discover novel anti-inflammatory drug candidates as COX-2 inhibitors from specific metabolites of Diospyros batokana (Ebenaceae);Biochemistry and Biophysics Reports;2024-09

4. Exploring novel Apalutamide analogues as potential therapeutics for prostate cancer: design, molecular docking investigations and molecular dynamics simulation;Frontiers in Chemistry;2024-08-06

5. Predicting Peptide Permeability Across Diverse Barriers: A Systematic Investigation;Molecular Pharmaceutics;2024-07-20