Synthetic oligodeoxynucleotide purification by capping failure sequences with a methacrylamide phosphoramidite followed by polymerization-Reference-Cited by-同舟云学术

Synthetic oligodeoxynucleotide purification by capping failure sequences with a methacrylamide phosphoramidite followed by polymerization

Published:2014 Issue:17 Volume:4 Page:8746-8757
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Pokharel Durga¹²³,Yuan Yinan⁴²³,Fueangfung Suntara¹²³,Fang Shiyue¹²³

Affiliation:

1. Department of Chemistry

2. Michigan Technological University

3. Houghton, USA

4. School of Forest Resources and Environmental Science

Abstract

Synthetic oligodeoxynucleotides are simply purified by capping failure sequences with a methacrylamide phosphoramidite, co-polymerization with N,N-dimethylacrylamide and extraction with water.

Funder

NSF Office of the Director

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C3RA46986G

Reference29 articles.

1. Recent Patents on Oligonucleotide Synthesis and Gene Synthesis

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4. Purification of DMT-On Oligonucleotide by Simulated Moving-Bed (SMB) Chromatography

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