Design, synthesis and biological evaluation of novel Schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel Schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents

Published:2017 Issue:5 Volume:8 Page:907-916
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Duan Jun-Rong¹²³⁴⁵,Liu Han-Bo¹²³⁴⁵,Jeyakkumar Ponmani¹²³⁴⁵,Gopala Lavanya¹²³⁴⁵,Li Shuo⁶⁷⁸⁹,Geng Rong-Xia¹²³⁴⁵,Zhou Cheng-He¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Bioorganic & Medicinal Chemistry

2. Key Laboratory of Applied Chemistry of Chongqing Municipality

3. School of Chemistry and Chemical Engineering

4. Southwest University

5. Chongqing 400715

6. School of Chemical Engineering

7. Chongqing University of Technology

8. Chongqing 400054

9. PR China

Abstract

Synthesis of a series of Schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents, and preliminary interactions with DNA indicated the possible interaction mechanism.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00688D

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