Metal-free oxidative trifluoromethylation of indoles with CF3SO2Na on the C2 position-Reference-Cited by-同舟云学术

Metal-free oxidative trifluoromethylation of indoles with CF3SO2Na on the C2 position

Published:2019 Issue:60 Volume:9 Page:35098-35101
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Xie Jiao-Jiao¹²³⁴⁵^ORCID,Wang Zhi-Qing¹²³⁴⁵,Jiang Guo-Fang¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. Hunan University

4. Changsha 410082

5. P. R. China

Abstract

An efficient method of synthesizing 2-trifluoromethylindoles from indoles with easy-to-handle, cheap and low-toxic CF₃SO₂Na under metal-free conditions is described, which selectively introduces trifluoromethyl to indoles on the C2 position.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA07785E

Reference45 articles.

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