Affiliation:
1. Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology-Banaras Hindu University (IIT-BHU)
2. CSIR-Institute of Himalayan Bioresource Technology
Abstract
AbstractA photoinduced approach for regioselective C-2 trifluoromethylation of indoles was achieved with CF3SO2Na under UV light irradiation (360–365 nm) at ambient conditions without any external photo activator. The key steps involve the in situ conversion of CF3SO2Na reagent to CF3
• radical under oxygen or air and UV irradiation. This proficient method has the advantages of mild reaction conditions, fair substrate tolerability, and gram scalability.
Funder
Department of Biotechnology, Ministry of Science and Technology, India
Subject
Organic Chemistry,Catalysis