An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1,4-disubstituted-1,2,3-triazoles-Reference-Cited by-同舟云学术

An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1,4-disubstituted-1,2,3-triazoles

Published:2014 Issue:80 Volume:50 Page:11926-11929
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Ali Akbar¹²³,Corrêa Arlene G.¹²³,Alves Diego¹⁴⁵,Zukerman-Schpector Julio¹²³,Westermann Bernhard⁶⁷⁸,Ferreira Marco A. B.¹²³,Paixão Márcio W.¹²³

Affiliation:

1. Department of Chemistry

2. Universidade Federal de São Carlos (UFSCar)

3. São Carlos, Brazil

4. Universidade Federal de Pelotas (UFPel)

5. Pelotas, Brazil

6. Department of Bioorganic Chemistry

7. Leibniz-Institute of Plant Biochemistry

8. Halle, Germany

Abstract

A simple and efficient metal-free methodology for the regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles by applying a novel inverse electron-demand-1,3-dipolar cycloaddition approach has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC04678A

Reference72 articles.

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2. Copper-Free Azide–Alkyne Cycloadditions: New Insights and Perspectives

3. Synthesis of Densely Functionalized 3a,4-Dihydro-1H-Pyrrolo[1,2-b]Pyrazoles via Base Mediated Domino Reaction of Vinyl Malononitriles with 1,2-Diaza-1,3-dienes

4. α,α-Dicyanoalkenes: versatile vinylogous nucleophiles for organic synthesis

5. Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

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