Design and synthesis of VEGFR-2 tyrosine kinase inhibitors as potential anticancer agents by virtual based screening-Reference-Cited by-同舟云学术

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Design and synthesis of VEGFR-2 tyrosine kinase inhibitors as potential anticancer agents by virtual based screening

Published:2015 Issue:70 Volume:5 Page:56724-56771
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Patel Harun M.¹²³⁴⁵,Bari Pankaj⁵⁶⁷⁸,Karpoormath Rajshekhar¹²³⁴,Noolvi Malleshappa⁵⁹¹⁰⁸,Thapliyal Neeta¹²³⁴,Surana Sanjay⁵⁶⁷⁸,Jain Pritam⁵⁶⁷⁸

Affiliation:

1. Dept. of Pharmaceutical Chemistry

2. University of KwaZulu-Natal (Westville Campus)

3. Durban-4000

4. South Africa

5. Department of Pharmaceutical Chemistry

6. R.C. Patel College of Pharmacy

7. Dhule 425405

8. India

9. Shree Dhanvantary Pharmacy College

10. Surat-3941110

Abstract

Design and synthesis of VEGFR-2 tyrosine kinase inhibitors as potential anticancer agents has been done by a virtual based screening approach.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA05277G

Reference36 articles.

1. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors

2. Discovery of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor

3. Discovery and molecular docking of quinolyl-thienyl chalcones as anti-angiogenic agents targeting VEGFR-2 tyrosine kinase

4. VEGF and the quest for tumour angiogenesis factors

5. The biology of VEGF and its receptors

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3. New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies;Journal of Biomolecular Structure and Dynamics;2023-12-15

4. Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies;European Journal of Medicinal Chemistry;2023-11

5. Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies;Journal of Enzyme Inhibition and Medicinal Chemistry;2022-08-18

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