Protein–protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and prediction-Reference-Cited by-同舟云学术

Protein–protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and prediction

Published:2023 Issue:3 Volume:4 Page:192-215
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Rui Huan¹^ORCID,Ashton Kate S.²,Min Jaeki³^ORCID,Wang Connie⁴,Potts Patrick Ryan³^ORCID

Affiliation:

1. Center for Research Acceleration by Digital Innovation, Amgen Research, Thousand Oaks, CA 91320, USA

2. Medicinal Chemistry, Amgen Research, Thousand Oaks, CA 91320, USA

3. Induced Proximity Platform, Amgen Research, Thousand Oaks, CA 91320, USA

4. Digital, Technology & Innovation, Amgen, Thousand Oaks, CA 91320, USA

Abstract

This review surveys molecular glue-induced ternary complexes in the PDB and provides an overview of computational methods that can be utilized to predict them.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CB/D2CB00207H

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