Solid state thermomechanical engineering of high-quality pharmaceutical salts via solvent free continuous processing-Reference-Cited by-同舟云学术

Solid state thermomechanical engineering of high-quality pharmaceutical salts via solvent free continuous processing

Published:2020 Issue:2 Volume:22 Page:540-549
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Mithu Md Sadeque Hossain¹²³⁴⁵^ORCID,Ross Steven A.¹²³⁴⁵^ORCID,Alexander Bruce D.¹²³⁴^ORCID,Douroumis Dennis¹²³⁴⁶^ORCID

Affiliation:

1. Faculty of Engineering and Science

2. University of Greenwich

3. Chatham Maritime

4. UK

5. Cubi-Tech Extrusion Ltd.

6. CIPER Centre for Innovation and Process Engineering Research

Abstract

Solvent-free, continuous processing of high-quality pharmaceutical salts through via hot-melt extrusion as an alternative to solvent based approaches.

Funder

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/GC/C9GC03528A

Reference56 articles.

1. Guidance for industry: classification of pharmaceutical co-crystals. FDA guidance 2016, http://www.fda.gov/downloads/Drugs/Guidances/UCM516813.pdf

2. Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges

3. Salt screening and characterization of ciprofloxacin

4. Salt formation to improve drug solubility

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