Continuous Synthesis of Cinnarizine Salt with Malic Acid by Applying Green Chemistry Using Water-Assisted Twin Screw Extrusion-Reference-Cited by-同舟云学术

Continuous Synthesis of Cinnarizine Salt with Malic Acid by Applying Green Chemistry Using Water-Assisted Twin Screw Extrusion

Published:2023-08-30 Issue:10 Volume:20 Page:5160-5172
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Vasoya Jaydip M.¹,Lee Hung Lin¹²^ORCID,Lee Tu¹²^ORCID,Serajuddin Abu T. M.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John’s University, 8000 Utopia Parkway, Queens, New York 11439, United States

2. Department of Chemical and Materials Engineering, National Central University, 300 Zhongda Road, Zhongli District, Taoyuan City 320317, Taiwan, ROC

Funder

Ministry of Science and Technology, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00511

Reference29 articles.

1. Advanced Methodologies for Pharmaceutical Salt Synthesis

2. Salt formation to improve drug solubility

3. Food and Drug Administration. Regulatory Classification of Pharmaceutical Co-Crystals Guidance for Industry Center for Drug Evaluation and Research (CDER): USA; 2018.

4. Salt Selection and Simultaneous Polymorphism Assessment via High-Throughput Crystallization: The Case of Sertraline

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