A superporous and pH-sensitive hydrogel from Salvia hispanica (chia) seeds: stimuli responsiveness, on–off switching, and pharmaceutical applications

Author:

Khatoon Maria1,Ali Arshad1,Hussain Muhammad Ajaz2ORCID,Haseeb Muhammad Tahir3,Sher Muhammad1,Alsaidan Omar A.4,Muhammad Gulzar5,Hussain Syed Zajif6ORCID,Hussain Irshad6ORCID,Bukhari Syed Nasir Abbas7

Affiliation:

1. Institute of Chemistry, University of Sargodha, Sargodha 40100, Pakistan

2. Centre for Organic Chemistry, School of Chemistry, University of the Punjab, Lahore 54590, Pakistan

3. College of Pharmacy, University of Sargodha, Sargodha 40100, Pakistan

4. Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72388, Aljouf, Saudi Arabia

5. Department of Chemistry, Government College University Lahore, Lahore 54000, Pakistan

6. Department of Chemistry, SBA School of Science & Engineering, Lahore University of Management Sciences, Lahore Cantt. 54792, Pakistan

7. Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, 72388, Saudi Arabia

Abstract

The chia seeds hydrogel (CSH) is a superporous, superabsorbent, haemocompatible, and smart biomaterial exhibiting stimuli-responsive swelling–deswelling behavior and sustained drug release.

Funder

Ministry of Education – Kingdom of Saudi Arabi

Publisher

Royal Society of Chemistry (RSC)

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