Fabricating a PDA-NOate@CuS coated NIR-activatable titanium implant to realize simultaneous antiinfection and osseointegration

Author:

Liu Jiahuan1,Li Xiaowan2,Xie Shangyu2,Ma Ruirui2,Wang Hongfei3,Ban Shurong1,Zhang Chengwu24,Guo Lixia12ORCID

Affiliation:

1. School of Pharmacy, Shanxi Medical University, Taiyuan 030001, P. R. China

2. School of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, P. R. China

3. Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, P. R. China

4. Precise Diagnosis and Treatment of Neurodegenerative Diseases Engineering Research Center, Jinzhong 030606, P. R. China

Abstract

A good biocompatible multifunctional Ti implant was constructed, which exhibits synergistic antibacterial activity through photothermal and NO effects, and promotes osseointegration.

Funder

Natural Science Foundation of Shanxi Province

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

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