Design, synthesis and antiproliferative screening of newly synthesized acrylate derivatives as potential anticancer agents

Author:

Alshaya Dalal Sulaiman1,Tawakul Rana M. O.2,Zaki Islam3ORCID,Abu Almaaty Ali H.2,Fayad Eman4,Abd El-Aziz Yasmin M.2

Affiliation:

1. Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

2. Zoology Department, Faculty of Science, Port Said University, Port Said 42526, Egypt

3. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt

4. Department of Biotechnology, Faculty of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

Abstract

A sequence of novel acrylic acids and acrylic esters has been synthesized and evaluated for in vitro cytotoxicity against MCF-7 breast cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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