Design, synthesis and antiproliferative screening of newly synthesized coumarin-acrylamide hybrids as potential cytotoxic and apoptosis inducing agents-Reference-Cited by-同舟云学术

Design, synthesis and antiproliferative screening of newly synthesized coumarin-acrylamide hybrids as potential cytotoxic and apoptosis inducing agents

Published:2023 Issue:46 Volume:13 Page:32547-32557
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Abd El-Lateef Hany M.¹²,Abdel Ghany Lina M. A.³,Saleem Rasha Mohammed⁴,Ahmed Maghrabi Ali Hassan⁵,Yahya Alahdal Maryam Abdulrahman⁵,Khalifa Ali Eman Hussain⁶,Beshay Botros Y.⁷,Zaki Islam⁸^ORCID,Masoud Reham E.⁹

Affiliation:

1. Department of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia

2. Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt

3. Pharmaceutical Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Egypt

4. Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha 65431, Saudi Arabia

5. Department of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah 24381, Saudi Arabia

6. Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Saudi Arabia

7. Pharmaceutical Sciences (Pharmaceutical Chemistry) Department, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, Alexandria, Egypt

8. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said, Egypt

9. Clinical Pharmacology Department, Faculty of Medicine, Port Said University, Port Said 42526, Egypt

Abstract

A sequence of novel coumarin-acrylamide hybrids has been synthesized and evaluated for their in vitro cytotoxicity against HepG2 liver cancer cells.

Funder

King Faisal University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06644D

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