Synthesis and anticancer activity of carbosilane metallodendrimers based on arene ruthenium(ii) complexes-Reference-Cited by-同舟云学术

Synthesis and anticancer activity of carbosilane metallodendrimers based on arene ruthenium(ii) complexes

Published:2016 Issue:16 Volume:45 Page:7049-7066
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Maroto-Díaz Marta¹²³⁴⁵,Elie Benelita T.⁶⁷⁸⁹¹⁰,Gómez-Sal Pilar¹²³⁴,Pérez-Serrano Jorge¹¹²³⁴,Gómez Rafael¹²³⁴⁵,Contel María⁶⁷⁸⁹¹⁰,Javier de la Mata F.¹²³⁴⁵

Affiliation:

1. Departamento de Química Orgánica y Química Inorgánica

2. Universidad de Alcalá

3. E-28871 Alcalá de Henares

4. Spain

5. Networking Research Center on Bioengineering

6. Department of Chemistry

7. Brooklyn College and The Graduate Center

8. The City University of New York

9. Brooklyn

10. USA

11. Departamento de Biomedicina y Biotecnología

Abstract

Carbosilane-based ruthenium dendrimers have been tested as anticancer agents. These metallodendrimers are active against a number of cisplatin resistant cell lines in the low micromolar range while showing a dendritic effect.

Funder

Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina

Consejería de Sanidad, Comunidad de Madrid

Secretaría de Estado de Investigación, Desarrollo e Innovación

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C6DT00465B

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