Synthesis and studies of aqueous-stable diruthenium aminocarbyne complexes uncovered an <i>N</i>-indolyl derivative as a prospective anticancer agent-Reference-Cited by-同舟云学术

Synthesis and studies of aqueous-stable diruthenium aminocarbyne complexes uncovered an N-indolyl derivative as a prospective anticancer agent

Published:2024 Issue:10 Volume:11 Page:2841-2862
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Fiaschi Matteo¹,Vančo Ján²^ORCID,Biancalana Lorenzo¹^ORCID,Malina Tomáš²,Dvořák Zdeněk³,Funaioli Tiziana¹,Zacchini Stefano⁴^ORCID,Guelfi Massimo¹,Trávníček Zdeněk²^ORCID,Marchetti Fabio¹^ORCID

Affiliation:

1. Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute, Palacký University, Šlechtitelů 27, CZ-779 00 Olomouc, Czech Republic

2. University of Pisa, Department of Chemistry and Industrial Chemistry, Via G. Moruzzi 13, I-56124 Pisa, Italy

3. Department of Cell Biology and Genetics, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-779 00 Olomouc, Czech Republic

4. University of Bologna, Dipartimento di Chimica Industriale “Toso Montanari”, Via Gobetti 85, I-40129 Bologna, Italy

Abstract

Within a set of diruthenium aminocarbyne analogues, an indolyl-decorated complex, displaying optimal physicochemical properties, exhibited potent in vitro cytotoxicity against a panel of cancer cell lines, coupled with remarkable selectivity.

Funder

Università di Pisa

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QI/D4QI00096J

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3. Correction: Synthesis and studies of aqueous-stable diruthenium aminocarbyne complexes uncovered an N-indolyl derivative as a prospective anticancer agent;Inorganic Chemistry Frontiers;2024