Synthesis and antibiotic activity of oxazolidinone–catechol conjugates against Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Synthesis and antibiotic activity of oxazolidinone–catechol conjugates against Pseudomonas aeruginosa

Published:2015 Issue:47 Volume:13 Page:11567-11579
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Paulen Aurélie¹²³⁴⁵,Gasser Véronique¹²³⁴⁵,Hoegy Françoise¹²³⁴⁵,Perraud Quentin¹²³⁴⁵,Pesset Bénédicte¹²³⁴⁵,Schalk Isabelle J.¹²³⁴⁵,Mislin Gaëtan L. A.¹²³⁴⁵

Affiliation:

1. Equipe Transport Membranaire Bactérien

2. Biotechnologie et Signalisation Cellulaire

3. UMR7242 Université de Strasbourg-CNRS

4. 67412 Illkirch Cedex

5. France

Abstract

An oxazolidinone antibiotic, conjugated to a catechol moiety, was shown to be at least eight times more active againstP. aeruginosa, when compared to the linezolid, used as a reference compound.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01859E

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1. Coevolution: Mankind and Microbes

2. New antibiotics for bad bugs: where are we?

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