In situ activation of benzyl alcohols with XtalFluor-E: formation of 1,1-diarylmethanes and 1,1,1-triarylmethanes through Friedel–Crafts benzylation-Reference-Cited by-同舟云学术

In situ activation of benzyl alcohols with XtalFluor-E: formation of 1,1-diarylmethanes and 1,1,1-triarylmethanes through Friedel–Crafts benzylation

Published:2015 Issue:8 Volume:13 Page:2243-2246
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Desroches Justine¹²³⁴⁵,Champagne Pier Alexandre¹²³⁴⁵,Benhassine Yasmine¹²³⁴⁵,Paquin Jean-François¹²³⁴⁵

Affiliation:

1. Canada Research Chair in Organic and Medicinal Chemistry

2. CGCC

3. PROTEO

4. Département de chimie

5. Université Laval

Abstract

The Friedel–Crafts benzylation of arenes using benzyl alcohols activated in situ with XtalFluor-E is described. A wide range of 1,1-diarylmethanes and 1,1,1-triarylmethanes were prepared under simple and mild conditions, without the need for a transition metal or a strong Lewis acid.

Funder

Natural Sciences and Engineering Research Council of Canada

Canada Foundation for Innovation

Canada Research Chairs

Fonds QuÃ©bÃ©cois de la Recherche sur la Nature et les Technologies

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB02655A

Reference31 articles.