Selective reduction of nitroarenes using Ru/C and CaH2

Author:

Robles-Henríquez Ramiro1,Chávez-Vega Tomás1,Gallardo-Fuentes Sebastián2,Lodeiro Lucas1ORCID,Lühr Susan1ORCID,Vilches-Herrera Marcelo1ORCID

Affiliation:

1. Chemistry Department, Faculty of Science, University of Chile, Las Palmeras 3425, Ñuñoa, Santiago, Chile

2. Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Avenida Universidad 330, Curauma, Valparaíso, Chile

Abstract

Highly selective reduction of nitro compounds using CaH2 and Ru/C in 2-MeTHF is reported, in most of the cases without the need for further purification.

Funder

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference87 articles.

1. H. K.Porter , in Organic Reactions , John Wiley & Sons , Hoboken,NJ , 2011 , p. 455

2. N.Ono , The Nitro Group in Organic Synthesis , John Wiley & Sons , New York, NY , 2001

3. F.Ullmann , W.Gerhartz , Y. S.Yamamoto , F. T.Campbell , R.Pfefferkorn and J. F.Rounsaville , Ullmann's Encyclopedia of Industrial Chemistry , Verlag Chemie , Weinheim, Germany , 2012 , vol. A2 , pp. 647–718

4. P. N.Rylander , Catalytic Hydrogenation in Organic Syntheses , Academic Press , 1979

5. S.Nishimura , Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis , John Wiley & Sons , 2001

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