Amyloid β-peptides 1–40 and 1–42 form oligomers with mixed β-sheets
Author:
Affiliation:
1. Department of Biochemistry and Biophysics
2. Stockholm University
3. Arrhenius Laboratories
4. 10691 Stockholm
5. Sweden
6. Department of Medical Biochemistry and Biophysics
7. Umeå University
8. 90187 Umeå
Abstract
Aβ40 and Aβ42 co-aggregate and form oligomers with mixed β-sheets as revealed by isotope-edited infrared spectroscopy.
Funder
Stiftelsen Lars Hiertas Minne
Alzheimerfonden
Knut och Alice Wallenbergs Stiftelse
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01743J
Reference52 articles.
1. Peptide Compositions of the Cerebrovascular and Senile Plaque Core Amyloid Deposits of Alzheimer′s Disease
2. Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo
3. Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
4. An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp 717 ) Mutants
5. Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Aβ42 and decreased Aβ40
Cited by 33 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Single-Molecule Characterization of Heterogeneous Oligomer Formation during Co-Aggregation of 40- and 42-Residue Amyloid-β;Journal of the American Chemical Society;2024-08-23
2. Computational analysis of hydrogen bonds network dynamics in the water layers surrounding Aβ(1-42) and Aβ(1-40) peptide dimers;Journal of Molecular Liquids;2024-08
3. Heterotypic Seeding Generates Mixed Amyloid Polymorphs;Small Science;2024-06-22
4. Heterotypic Seeding Generates Mixed Amyloid Polymorphs;2024-03-17
5. Amyloid β interferes with wound healing of brain microvascular endothelial cells by disorganizing the actin cytoskeleton;Experimental Cell Research;2024-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3