Synthesis of α-arylthioacetones using TEMPO as theC3synthonviaa reaction cascade of sequential oxidation, skeletal rearrangement and C–S bond formation

Author:

Zou Jiao-Xia1234ORCID,Jiang Yi1234ORCID,Lei Shuai1234,Yin Gao-Feng1234,Hu Xiao-Ling1234,Zhao Quan-Yi1234,Wang Zhen12345ORCID

Affiliation:

1. School of Pharmacy

2. Lanzhou University

3. Lanzhou 730000

4. China

5. Institution State Key Laboratory of Applied Organic Chemistry

Abstract

Here, we present an unprecedented pathway to α-arythioacetones from commercially available thiols and universally employed TEMPO and its analogues.

Funder

Recruitment Program of Global Experts

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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