Novel metal chelators thiosemicarbazones with activity at the σ2receptors and P-glycoprotein: an innovative strategy for resistant tumor treatment-Reference-Cited by-同舟云学术

Novel metal chelators thiosemicarbazones with activity at the σ2receptors and P-glycoprotein: an innovative strategy for resistant tumor treatment

Published:2015 Issue:125 Volume:5 Page:103131-103146
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pati Maria Laura¹²³⁴⁵,Niso Mauro¹²³⁴,Ferorelli Savina¹²³⁴,Abate Carmen¹²³⁴,Berardi Francesco¹²³⁴

Affiliation:

1. Dipartimento di Farmacia-Scienze del Farmaco

2. Università degli Studi di Bari ALDO MORO

3. I-70125 Bari

4. Italy

5. Division of Hepatobiliary, Pancreatic, and Gastrointestinal Surgery

Abstract

Novel multitarget thiosemicarbazones that bind simultaneously σ₂receptors and P-glycoprotein efflux pump and chelate metals were designed for resistant tumors treatment.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19857G

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