Development of <i>N</i>-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase-Reference-Cited by-同舟云学术

Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase

Published:2022-12-21 Issue:1 Volume:66 Page:235-250
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Intranuovo Francesca¹,Brunetti Leonardo¹^ORCID,DelRe Pietro²,Mangiatordi Giuseppe Felice²^ORCID,Stefanachi Angela¹^ORCID,Laghezza Antonio¹^ORCID,Niso Mauro¹,Leonetti Francesco¹,Loiodice Fulvio¹^ORCID,Ligresti Alessia³^ORCID,Kostrzewa Magdalena³,Brea Jose⁴⁵^ORCID,Loza Maria Isabel⁴⁵^ORCID,Sotelo Eddy⁶^ORCID,Saviano Michele⁷^ORCID,Colabufo Nicola Antonio¹^ORCID,Riganti Chiara⁸^ORCID,Abate Carmen¹²^ORCID,Contino Marialessandra¹^ORCID

Affiliation:

1. Dipartimento di Farmacia-Scienze Del Farmaco, Università Degli Studi di Bari ALDO MORO, Via Orabona 4, Bari 70125, Italy

2. Institute of Crystallography, National Research Council of Italy, Via Amendola, 122/o, Bari 70126, Italy

3. Institute of Biomolecular Chemistry, National Research Council of Italy, Via Campi Flegrei 34, Pozzuoli 80078, Italy

4. Innopharma Screening Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Santiago de Compostela 15782, Spain

5. Department of Pharmacology, Pharmacy and Pharmaceutical Technology. School of Pharmacy, University of Santiago de Compostela, Santiago de Compostela 15782, Spain

6. ComBioMed Research Group, Centro de Química Biológica y Materiales Moleculares (CIQUS), University of Santiago de Compostela, Santiago de Compostela 15782, Spain

7. Institute of Crystallography, National Research Council of Italy, Via Vivaldi, 43, Caserta 81100, Italy

8. Dipartimento di Oncologia, Università Degli Studi di Torino, Torino 10126, Italy

Funder

Agencia Estatal de Investigaci?n

European Regional Development Fund

Compagnia di San Paolo

Xunta de Galicia

European Cooperation in Science and Technology

European Molecular Biology Organization

Publisher

American Chemical Society (ACS)

Subject