The lipidomic profile of the nanoparticle-biomolecule corona reflects the diversity of plasma lipids

Author:

Papafilippou Lana1ORCID,Nicolaou Anna23ORCID,Kendall Alexandra C.2ORCID,Camacho-Muñoz Dolores2ORCID,Hadjidemetriou Marilena1ORCID

Affiliation:

1. Nanomedicine Lab, Faculty of Biology, Medicine & Health, AV Hill Building, University of Manchester, Manchester Academic Healthy Science Centre, Manchester, M13 9PT, UK

2. Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Healthy Science Centre, Manchester, M13 9PT, UK

3. Lydia Becker Institute of Immunology and Inflammation, School of Biological Sciences, University of Manchester, Manchester, M13 9PT, UK

Abstract

Our work highlights the importance of multi-omics to comprehend the multi-molecular composition of the nanoparticle biomolecule corona and paves the way for the corona-enabled enrichment of blood-circulating disease-specific lipids.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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