Euphorbia tirucalli aqueous extract induces cytotoxicity, genotoxicity and changes in antioxidant gene expression in human leukocytes-Reference-Cited by-同舟云学术

Euphorbia tirucalli aqueous extract induces cytotoxicity, genotoxicity and changes in antioxidant gene expression in human leukocytes

Published:2015 Issue:3 Volume:4 Page:739-748
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Waczuk Emily Pansera¹²³,Kamdem Jean Paul⁴⁵⁶⁷³,Abolaji Amos Olalekan⁴⁵⁶⁷³,Meinerz Daiane Francine⁴⁵⁶⁷³,Caeran Bueno Diones⁴⁵⁶⁷³,do Nascimento Gonzaga Thallita Karla Silva⁴⁵⁶⁷³,do Canto Dorow Thais Scotti⁸⁶⁷³,Boligon Aline Augusti⁹⁶⁷³,Athayde Margareth Linde⁹⁶⁷³,da Rocha João Batista Teixeira⁴⁵⁶⁷³,Ávila Daiana Silva¹²³

Affiliation:

1. Universidade Federal do Pampa

2. CEP 97500-970 Uruguaiana

3. Brazil

4. Departamento de Química

5. Centro de Ciências Naturais e Exatas

6. Universidade Federal de Santa Maria

7. Santa Maria

8. Departamento de Biologia

9. Programa de Pós-Graduação em Ciências Farmacêuticas

Abstract

The medicinal use of Euphorbia tirucalli has to be made with caution, as our study indicates that the aqueous extract induces genotoxicity and cytotoxicity in human leukocytes

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TX/C4TX00122B

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1. Mechanisms and modifiers of methylmercury-induced neurotoxicity