Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays-Reference-Cited by-同舟云学术

Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays

Published:2020 Issue:2 Volume:20 Page:199-214
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Hardwick Rhiannon N.¹²³⁴^ORCID,Betts Catherine J.⁵⁶⁷⁸⁹,Whritenour Jessica¹⁰¹¹¹²⁴,Sura Radhakrishna¹³¹⁴¹⁵⁴,Thamsen Maike¹⁶²³⁴,Kaufman Elad H.¹⁷²³⁴,Fabre Kristin¹⁸¹⁹⁷⁸²⁰

Affiliation:

1. Translational Safety Sciences

2. Theravance Biopharma, US, Inc.

3. South San Francisco

4. USA

5. Pathology Sciences

6. Drug Safety and Metabolism

7. IMED Biotech Unit

8. AstraZeneca

9. Cambridge

10. Pfizer, Inc.

11. Drug Safety Research and Development

12. Groton

13. Preclinical Safety

14. Abbvie Inc.

15. North Chicago

16. Pharmacology

17. Biology

18. MPS Center of Excellence

19. Drug Safety & Metabolism

20. Waltham

Abstract

Selected skin MPS features desired to advance further adoption within the pharmaceutical industry.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00519F

Reference106 articles.

1. Epithelial Skin Biology

2. Matrix molecules and skin biology

3. Mechanical forces in skin disorders

4. In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

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