Microfluidic harvesting of breast cancer tumor spheroid-derived extracellular vesicles from immobilized microgels for single-vesicle analysis-Reference-Cited by-同舟云学术

Microfluidic harvesting of breast cancer tumor spheroid-derived extracellular vesicles from immobilized microgels for single-vesicle analysis

Published:2022 Issue:13 Volume:22 Page:2502-2518
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Rima Xilal Y.¹^ORCID,Zhang Jingjing¹,Nguyen Luong T. H.¹,Rajasuriyar Aaron¹,Yoon Min Jin¹,Chiang Chi-Ling¹,Walters Nicole¹,Kwak Kwang Joo²,Lee L. James¹²,Reátegui Eduardo¹³^ORCID

Affiliation:

1. William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA

2. Spot Biosystems Ltd., Palo Alto, CA 94301, USA

3. Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA

Abstract

A novel microfluidic system for the low-volume harvesting of extracellular vesicles from breast cancer tumor spheroids encapsulated within immobilized hydrogel microbioreactors for downstream single-vesicle analyses.

Funder

National Center for Advancing Translational Sciences

Ohio State University

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC01053K

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