The quantum dot <i>vs.</i> organic dye conundrum for ratiometric FRET-based biosensors: which one would you chose?-Reference-Cited by-同舟云学术

The quantum dot vs. organic dye conundrum for ratiometric FRET-based biosensors: which one would you chose?

Published:2022 Issue:22 Volume:13 Page:6715-6731
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Grazon Chloé¹²³^ORCID,Chern Margaret⁴^ORCID,Lally Patrick⁵,Baer R. C.⁶⁷^ORCID,Fan Andy⁵^ORCID,Lecommandoux Sébastien²^ORCID,Klapperich Catherine⁵^ORCID,Dennis Allison M.⁴⁵^ORCID,Galagan James E.⁶⁵⁷^ORCID,Grinstaff Mark W.¹⁴⁵^ORCID

Affiliation:

1. Department of Chemistry, Boston University, Boston, MA 02215, USA

2. University Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629, F-33600, Pessac, France

3. University Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, F-33400 Talence, France

4. Division of Materials Science and Engineering, Boston University, Boston, MA 02215, USA

5. Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA

6. Department of Microbiology, Boston University, Boston, MA 02118, USA

7. National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02118, USA

Abstract

We report a combined experimental and computational study to systematically compare the nature of the dye, i.e., organic fluorophore vs. inorganic nanoparticle, and the position of the FRET donor or acceptor on the biosensor performances.

Funder

National Institutes of Health

Uniformed Services University of the Health Sciences

Defense Advanced Research Projects Agency

Office of Naval Research

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC06921G