Behaviors of self-delivery lidocaine nano systems affected by intermolecular interaction-Reference-Cited by-同舟云学术

Behaviors of self-delivery lidocaine nano systems affected by intermolecular interaction

Published:2023 Issue:12 Volume:59 Page:1653-1656
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Tang Lei¹²^ORCID,Qin Feng³,Gong Deying¹²,Pan LiLi³,Zhou Changcui¹²,Ling Rui¹²,Shen Wenxue¹²,Fan Qin³,Yi Wenhao³,Wu Fengbo³,Wu Xiaoai³^ORCID,Zhang Weiyi¹²,Yang Jun¹²

Affiliation:

1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China

2. Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China

3. West China Hospital, Sichuan University, Chengdu 610041, P. R. China

Abstract

Nano systems self-assembled only by lidocaine salts exhibit unexpected unique behaviors in different local tissues based on their intermolecular interaction, and can achieve up to 7.8 h sensory block without excipient residue.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC06519C

Reference25 articles.

1. A Review of the Compatibility of Liposome Bupivacaine with Other Drug Products and Commonly Used Implant Materials

2. QSAR (quantitative structure-activity relationship) studies on local anesthetics

3. Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review

4. The Science of Local Anesthesia

5. Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants

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