Long-term sciatic nerve block led by a supramolecular arrangement of self-delivery local anesthetic nano systems-Reference-Cited by-同舟云学术

Long-term sciatic nerve block led by a supramolecular arrangement of self-delivery local anesthetic nano systems

Published:2023 Issue:54 Volume:59 Page:8400-8403
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Tang Lei¹²^ORCID,Qin Feng³,Gong Deying¹²,Dong Yu⁴^ORCID,Pan LiLi³,Zhou Changcui¹²,Yin Qinqin¹,Song Xinghai¹²,Ling Rui¹²,Huang Junlong¹²,Fan Qin³,Yi Wenhao³,Wu Fengbo³,Wu Xiaoai³^ORCID,Zhang Weiyi¹,Yang Jun¹²,Wang Ji-Yu⁵^ORCID

Affiliation:

1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China

2. Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China

3. West China Hospital, Sichuan University, Chengdu 610041, P. R. China

4. College of Chemistry and Life Science, Sichuan Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules, Chengdu Normal University, Chengdu, 611130, P. R. China

5. Department of Chemistry, Xihua University, Chengdu, P. R. China

Abstract

1e can self-assemble into vesicles in water and achieve a 43.2 h sensory block based on self-release and counter ion exchange inside nerve cells, which were affected by the gemini surfactant structure, pKa of the counter ions and π–π stacking.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC02269B

Reference20 articles.

1. New local anesthetics

2. Behaviors of self-delivery lidocaine nano systems affected by intermolecular interaction

3. A review of postoperative analgesia for breast cancer surgery

4. A comparison of epidural levobupivacaine and sufentanil with or without adrenaline for labour analgesia

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