The effectiveness of topical anti-inflammatory hormonal therapy in irritant contact dermatitis management in toddlers

Abstract

Pediatric skin has some peculiarities that may determine why children are more likely to develop some skin conditions. In pediatrics, contact dermatitis is one of the most prevalent skin diseases involving impaired epithelial barrier. To reduce skin inflammation, decrease in frequency, duration, and number of contacts with triggering factors along with skin barrier restoration are needed. The Anti-inflammatory hormonal topical therapy represents the main treatment method. This article demonstrated several clinical cases of contact dermatitis in toddlers that were treated with methylprednisolone aceponate accompanied by ceramides and showed high therapy effectiveness in toddlers. A case of treatment of a child aged 1 year, 3 months with asymmetrical widespread hyperemic spots on the back surface of the body, mainly in the lumbar region; a case of treatment of a 2-year-old child with multiple hyperemic spots located on the anterior and, to a greater extent, posterior surface of the lower extremities, having clear edges, accompanied by focal dryness and moderate peeling at the edges; as well as a case of treatment of a child aged 1 year 11 months with hyperemic asymmetrical dry spots of irregular shape on the posterior and medial surface of the left forearm, which tend to merge and have clear edges. The use of topical corticosteroid in combination with ceramides in pediatrics leads to effective and fast inflammation decrease along with visible skin restoration.