The effectiveness of external anti-inflammatory therapy for contact dermatitis in infants

Abstract

Contact dermatitis in paediatric population is a fairly common pathology, which occurs where the skin comes into contact with irritating factors. It refers to steroid-sensitive dermatoses, therefore, the prescription of topical glucocorticosteroids in this pathology is a proved method of treatment. 0.1% methylprednisolone aceponate cream that has anti-inflammatory and anti-allergic effects is a medium-potency effective topical glucocorticosteroid. In this article, the authors presented their own experience and clinical cases of the effective use of 0.1% methylprednisolone aceponate cream in contact dermatitis in paediatric population. The first clinical case demonstrates the use of 0.1% methylprednisolone aceponate cream once a day as part of the combination therapy in a 5-month-old baby with moderate contact dermatitis caused by cosmetic substances (massage oil). The treatment resulted in a pronounced improvement and the achievement of remission on the 8th day from the start of therapy. The second clinical case demonstrated the effectiveness of 0.1% methylprednisolone aceponate cream used once daily as part of the combination therapy in a 6-month-old baby with mild diaper contact dermatitis. The use of barrier medications (5% dexpanthenol ointment) for 3 days showed no positive changes, due to which 0.1% methylprednisolone aceponate cream was prescribed. The treatment resulted in the relief of acute signs of inflammation in the buttocks and complete remission on the 5th day of the use of the cream. The third clinical case demonstrated the effectiveness of topical glucocorticosteroid in the form of 0.1% methylprednisolone aceponate cream used once daily as part of combination therapy in a 4-month-old baby with severe contact dermatitis, which developed after washing the perineum and feet with laundry soap. The pronounced positive changes in the skin improvement process were observed from the 5th day of the therapy, and a remission was achieved on the 10th day of the therapy, which was demonstrated as relief of acute inflammatory process in the buttocks and lower extremities, and disappearance of itching and scratching. Overall, the above clinical cases showed the high effectiveness of the use of the topical glucocorticosteroid in the form of 0.1% methylprednisolone aceponate cream as part of the combination therapy of contact dermatitis in pediatric population (at any severity level).