Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
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Published:2017-09-04
Issue:10
Volume:49
Page:1450-1457
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Zhao WeiORCID, , Rasheed Asif, Tikkanen Emmi, Lee Jung-Jin, Butterworth Adam S, Howson Joanna M M, Assimes Themistocles L, Chowdhury Rajiv, Orho-Melander Marju, Damrauer Scott, Small Aeron, Asma Senay, Imamura Minako, Yamauch Toshimasa, Chambers John C, Chen Peng, Sapkota Bishwa R, Shah Nabi, Jabeen Sehrish, Surendran Praveen, Lu Yingchang, Zhang Weihua, Imran Atif, Abbas Shahid, Majeed Faisal, Trindade Kevin, Qamar Nadeem, Mallick Nadeem Hayyat, Yaqoob Zia, Saghir Tahir, Rizvi Syed Nadeem Hasan, Memon Anis, Rasheed Syed Zahed, Memon Fazal-ur-Rehman, Mehmood Khalid, Ahmed Naveeduddin, Qureshi Irshad Hussain, Tanveer-us-Salam , Iqbal Wasim, Malik Uzma, Mehra Narinder, Kuo Jane Z, Sheu Wayne H-H, Guo Xiuqing, Hsiung Chao A, Juang Jyh-Ming J, Taylor Kent D, Hung Yi-Jen, Lee Wen-Jane, Quertermous Thomas, Lee I-Te, Hsu Chih-Cheng, Bottinger Erwin P, Ralhan Sarju, Teo Yik Ying, Wang Tzung-Dau, Alam Dewan S, Di Angelantonio Emanuele, Epstein Steve, Nielsen Sune F, Nordestgaard Børge G, Tybjaerg-Hansen Anne, Young Robin, Benn Marianne, Frikke-Schmidt Ruth, Kamstrup Pia R, Jukema J Wouter, Sattar Naveed, Smit Roelof, Chung Ren-Hua, Liang Kae-Woei, Anand Sonia, Sanghera Dharambir K, Ripatti Samuli, Loos Ruth J F, Kooner Jaspal S, Tai E Shyong, Rotter Jerome I, Chen Yii-Der Ida, Frossard Philippe, Maeda Shiro, Kadowaki Takashi, Reilly Muredach, Pare Guillaume, Melander Olle, Salomaa Veikko, Rader Daniel J, Danesh John, Voight Benjamin F, Saleheen DanishORCID, , ,
Publisher
Springer Science and Business Media LLC
Reference54 articles.
1. Guariguata, L. et al. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res. Clin. Pract. 103, 137–149 (2014). 2. Xu, J., Murphy, S.L., Kochanek, K.D. & Bastian, B.A. Deaths: final data for 2013. Natl. Vital Stat. Rep. 64, 1–119 (2016). 3. Rao Kondapally Seshasai, S. et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N. Engl. J. Med. 364, 829–841 (2011). 4. Scott, R.A. et al. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Sci. Transl. Med. 8, 341ra76 (2016). 5. Morris, A.P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 44, 981–990 (2012).
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