Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity-Reference-Cited by-同舟云学术

Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity

Published:2016-06-13 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Hoefflin Rouven,Lahrmann Bernd,Warsow Gregor,Hübschmann Daniel,Spath Cathleen,Walter Britta,Chen Xin,Hofer Luisa,Macher-Goeppinger Stephan,Tolstov Yanis,Korzeniewski Nina,Duensing Anette,Grüllich Carsten,Jäger Dirk,Perner Sven,Schönberg Gita,Nyarangi-Dix Joanne,Isaac Sanjay,Hatiboglu Gencay,Teber Dogu,Hadaschik Boris,Pahernik Sascha,Roth Wilfried,Eils Roland,Schlesner Matthias,Sültmann Holger,Hohenfellner Markus,Grabe Niels,Duensing Stefan

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms11845.pdf

Reference38 articles.

1. Nowell, P. The clonal evolution of tumor cell populations. Science 194, 23–28 (1976).

2. Cahill, D. P., Kinzler, K. W., Vogelstein, B. & Lengauer, C. Genetic instability and darwinian selection in tumours. Trends Cell Biol. 9, M57–M60 (1999).

3. Burrell, R. A., McGranahan, N., Bartek, J. & Swanton, C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501, 338–345 (2013).

4. Fisher, R., Pusztai, L. & Swanton, C. Cancer heterogeneity: implications for targeted therapeutics. Br. J. Cancer 108, 479–485 (2013).

5. Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366, 883–892 (2012).

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Immune landscape of renal cell carcinoma with metastasis to the pancreas;Urologic Oncology: Seminars and Original Investigations;2024-11

2. Region of interest localization, tissue storage time, and antibody binding density—a technical note on the GeoMx® Digital Spatial Profiler;Immuno-Oncology and Technology;2024-09

3. Digital spatial profiling identifies the tumor center as a topological niche in prostate cancer characterized by an upregulation of BAD;Scientific Reports;2024-08-31

4. Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer;Cell Reports;2024-08

5. Heterogeneity generating capacity in tumorigenesis and cancer therapeutics;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-06