The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

Author:

Gupta Piyush B,Kuperwasser Charlotte,Brunet Jean-Philippe,Ramaswamy Sridhar,Kuo Wen-Lin,Gray Joe W,Naber Stephen P,Weinberg Robert A

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference42 articles.

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2. Beddingfield, F.C., III. The melanoma epidemic: res ipsa loquitur . Oncologist 8, 459–465 (2003).

3. Bartkova, J. et al. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res. 56, 5475–5483 (1996).

4. Omholt, K., Platz, A., Kanter, L., Ringborg, U. & Hansson, J. NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression. Clin. Cancer Res. 9, 6483–6488 (2003).

5. Chin, L. The genetics of malignant melanoma: lessons from mouse and man. Nat. Rev. Cancer 3, 559–570 (2003).

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