ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation-Reference-Cited by-同舟云学术

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Published:2008-01-20 Issue:2 Volume:10 Page:138-148
ISSN:1465-7392
Container-title:Nature Cell Biology
language:en
Short-container-title:Nat Cell Biol

Author:

Yang Jer-Yen,Zong Cong S.,Xia Weiya,Yamaguchi Hirohito,Ding Qingqing,Xie Xiaoming,Lang Jing-Yu,Lai Chien-Chen,Chang Chun-Ju,Huang Wei-Chien,Huang Hsin,Kuo Hsu-Ping,Lee Dung-Fang,Li Long-Yuan,Lien Huang-Chun,Cheng Xiaoyun,Chang King-Jen,Hsiao Chwan-Deng,Tsai Fuu-Jen,Tsai Chang-Hai,Sahin Aysegul A.,Muller William J.,Mills Gordon B.,Yu Dihua,Hortobagyi Gabriel N.,Hung Mien-Chie

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Link

http://www.nature.com/articles/ncb1676.pdf

Reference41 articles.

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2. Vogelstein, B. & Kinzler, K. W. Cancer genes and the pathways they control. Nature Med. 10, 789–799 (2004).

3. Yoon, S. & Seger, R. The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24, 21–44 (2006).

4. Kolch, W. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nature Rev. Mol. Cell Biol. 6, 827–837 (2005).

5. Thompson, N. & Lyons, J. Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery. Curr. Opin. Pharmacol. 5, 350–356 (2005).

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