Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase-Reference-Cited by-同舟云学术

Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase

Published:2016-12 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Eggenschwiler Reto,Moslem Mohsen,Fráguas Mariane Serra,Galla Melanie,Papp Oliver,Naujock Maximilian,Fonfara Ines,Gensch Ingrid,Wähner Annabell,Beh-Pajooh Abbas,Mussolino Claudio,Tauscher Marcel,Steinemann Doris,Wegner Florian,Petri Susanne,Schambach Axel,Charpentier Emmanuelle,Cathomen Toni,Cantz Tobias

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep38198.pdf

Reference34 articles.

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3. Hendel, A. et al. Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. Cell Rep 7, 293–305, doi: 10.1016/j.celrep.2014.02.040 (2014).

4. Papamichos-Chronakis, M. & Peterson, C. L. Chromatin and the genome integrity network. Nat Rev Genet 14, 62–75, doi: 10.1038/nrg3345 (2013).

5. Kuhar, R. et al. Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks. Nucleic Acids Res 42, e4, doi: 10.1093/nar/gkt872 (2014).

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