Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
-
Published:2015-06-12
Issue:1
Volume:6
Page:
-
ISSN:2041-1723
-
Container-title:Nature Communications
-
language:en
-
Short-container-title:Nat Commun
Author:
Draisma Harmen H. M., Pool René, Kobl Michael, Jansen Rick, Petersen Ann-Kristin, Vaarhorst Anika A. M., Yet Idil, Haller Toomas, Demirkan Ayşe, Esko Tõnu, Zhu Gu, Böhringer Stefan, Beekman Marian, van Klinken Jan Bert, Römisch-Margl Werner, Prehn Cornelia, Adamski Jerzy, de Craen Anton J. M., van Leeuwen Elisabeth M., Amin Najaf, Dharuri Harish, Westra Harm-Jan, Franke LudeORCID, de Geus Eco J. C., Hottenga Jouke Jan, Willemsen Gonneke, Henders Anjali K., Montgomery Grant W., Nyholt Dale R., Whitfield John B.ORCID, Penninx Brenda W., Spector Tim D., Metspalu Andres, Eline Slagboom P., van Dijk Ko WillemsORCID, ‘t Hoen Peter A. C., Strauch Konstantin, Martin Nicholas G., van Ommen Gert-Jan B.ORCID, Illig Thomas, Bell Jordana T., Mangino Massimo, Suhre KarstenORCID, McCarthy Mark I., Gieger Christian, Isaacs Aaron, van Duijn Cornelia M., Boomsma Dorret I.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference52 articles.
1. Suhre, K. & Gieger, C. Genetic variation in metabolic phenotypes: study designs and applications. Nat. Rev. Genet. 13, 759–769 (2012). 2. Suhre, K. et al. Human metabolic individuality in biomedical and pharmaceutical research. Nature 477, 54–60 (2011). 3. Nicholson, G. et al. A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet. 7, e1002270 (2011). 4. Illig, T. et al. A genome-wide perspective of genetic variation in human metabolism. Nat. Genet. 42, 137–141 (2010). 5. Gieger, C. et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4, e1000282 (2008).
Cited by
174 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|