A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis-Reference-Cited by-同舟云学术

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

Published:2009-06-14 Issue:7 Volume:15 Page:781-787
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Muchamuel Tony,Basler Michael,Aujay Monette A,Suzuki Erika,Kalim Khalid W,Lauer Christoph,Sylvain Catherine,Ring Eileen R,Shields Jamie,Jiang Jing,Shwonek Peter,Parlati Francesco,Demo Susan D,Bennett Mark K,Kirk Christopher J,Groettrup Marcus

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.1978.pdf

Reference40 articles.

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3. Borissenko, L. & Groll, M. 20S proteasome and its inhibitors: crystallographic knowledge for drug development. Chem. Rev. 107, 687–717 (2007).

4. Kloetzel, P.M. & Ossendorp, F. Proteasome and peptidase function in MHC-class-I–mediated antigen presentation. Curr. Opin. Immunol. 16, 76–81 (2004).

5. Griffin, T.A. et al. Immunoproteasome assembly: cooperative incorporation of interferon γ (IFN-γ)-inducible subunits. J. Exp. Med. 187, 97–104 (1998).

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