The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38SAPK pathway-Reference-Cited by-同舟云学术

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The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38SAPK pathway

Published:2012-04-23 Issue:9 Volume:32 Page:1135-1143
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Hennigan R F,Moon C A,Parysek L M,Monk K R,Morfini G,Berth S,Brady S,Ratner N

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2012135.pdf

Reference54 articles.

1. Rouleau GA, Merel P, Lutchman M, Sanson M, Zucman J, Marineau C et al. Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature 1993; 363: 515–521.

2. MacCollin M, Mohney T, Trofatter J, Wertelecki W, Ramesh V, Gusella J . DNA diagnosis of neurofibromatosis 2. Altered coding sequence of the merlin tumor suppressor in an extended pedigree. JAMA 1993; 270: 2316–2320.

3. Ammoun S, Hanemann CO . Emerging therapeutic targets in schwannomas and other merlin-deficient tumors. Nat Rev Neurol [Review] 2011; 7: 392–399.

4. McClatchey AI . Merlin and ERM proteins: unappreciated roles in cancer development? Nat Rev Cancer 2003; 3: 877–883.

5. Giovannini M, Robanus-Maandag E, van der Valk M, Niwa-Kawakita M, Abramowski V, Goutebroze L et al. Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Genes Dev 2000; 14: 1617–1630.

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