Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity-Reference-Cited by-同舟云学术

Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity

Published:2012-04-23 Issue:9 Volume:32 Page:1144-1154
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Lee P-C,Lee H-J,Kakadiya R,Sanjiv K,Su T-L,Lee T-C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2012133.pdf

Reference62 articles.

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2. Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM . Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006; 5: 219–234.

3. Goldstein LJ, Galski H, Fojo A, Willingham M, Lai SL, Gazdar A et al. Expression of a multidrug resistance gene in human cancers. J Natl Cancer Inst 1989; 81: 116–124.

4. Roninson IB, Chin JE, Choi KG, Gros P, Housman DE, Fojo A et al. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc Natl Acad Sci USA 1986; 83: 4538–4542.

5. Ford JM, Hait WN . Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 1990; 42: 155–199.

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