1. Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan, R.O.C.
2. Division of General Surgery, Department of Surgery, Ditmanson Medical Foundation Chia‑Yi Christian Hospital, Chiayi 600566, Taiwan, R.O.C.
3. Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan, R.O.C.
4. Center of Applied Nanomedicine, National Cheng Kung University, Tainan 701401, Taiwan, R.O.C.
5. Department of Chemistry, College of Sciences, Chinese Culture University, Taipei 111396, Taiwan, R.O.C.