The fusion pores of Ca2+-triggered exocytosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/nsmb.1449.pdf
Reference83 articles.
1. Chandler, D.E. & Heuser, J.E. Arrest of membrane fusion events in mast cells by quick-freezing. J. Cell Biol. 86, 666–674 (1980).
2. Heuser, J.E. & Reese, T.S. Structural changes after transmitter release at the frog neuromuscular junction. J. Cell Biol. 88, 564–580 (1981).
3. Lindau, M. & Almers, W. Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion. Curr. Opin. Cell Biol. 7, 509–517 (1995).
4. Klyachko, V.A. & Jackson, M.B. Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals. Nature 418, 89–92 (2002). This study revealed capacitance steps of small clear vesicles and showed that they undergo kiss-and-run by forming much smaller fusion pores.
5. Breckenridge, L.J. & Almers, W. Currents through the fusion pore that forms during exocytosis of a secretory granule. Nature 328, 814–817 (1987). The first measurement of fusion pore conductance gave a value in the range of ion-channel conductances.
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