Nanoscale structural response of biomimetic cell membranes to controlled dehydration

Author:

Krok Emilia1ORCID,Franquelim Henri G.23ORCID,Chattopadhyay Madhurima1ORCID,Orlikowska-Rzeznik Hanna1ORCID,Schwille Petra2ORCID,Piatkowski Lukasz1ORCID

Affiliation:

1. Poznan University of Technology, Faculty of Materials Engineering and Technical Physics, Institute of Physics, Piotrowo 3, 60-965 Poznan, Poland

2. Department of Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany

3. Leipzig University, Research and Transfer Center for Bioactive Matter, Deutscher Platz 5, 04103 Leipzig, Germany

Abstract

Reducing the hydration state of the membrane leads to an enhanced mixing of lipids characteristic of the liquid-disordered phase with those forming the liquid-ordered phase, and to the decrease in the hydrophobic mismatch between the two phases.

Funder

European Molecular Biology Organization

Fundacja na rzecz Nauki Polskiej

Ministerstwo Edukacji i Nauki

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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