Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling-Reference-Cited by-同舟云学术

Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling

Published:2017-03-09 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Arnold Philipp,Boll Inga,Rothaug Michelle,Schumacher Neele,Schmidt Frederike,Wichert Rielana,Schneppenheim Janna,Lokau Juliane,Pickhinke Ute,Koudelka Tomas,Tholey Andreas,Rabe Björn,Scheller Jürgen,Lucius Ralph,Garbers Christoph,Rose-John Stefan,Becker-Pauly Christoph

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep44053.pdf

Reference80 articles.

1. Stöcker, W. et al. The metzincins–topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases. Protein Sci 4, 823–840, doi: 10.1002/pro.5560040502 (1995).

2. Broder, C. & Becker-Pauly, C. The metalloproteases meprin alpha and meprin beta: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis. Biochem J 450, 253–264, doi: 10.1042/BJ20121751 (2013).

3. Tang, J. & Bond, J. S. Maturation of secreted meprin alpha during biosynthesis: role of the furin site and identification of the COOH-terminal amino acids of the mouse kidney metalloprotease subunit. Arch Biochem Biophys 349, 192–200, doi: 10.1006/abbi.1997.0453 (1998).

4. Becker, C. et al. Differences in the activation mechanism between the alpha and beta subunits of human meprin. Biol Chem 384, 825–831, doi: 10.1515/BC.2003.092 (2003).

5. Bertenshaw, G. P., Norcum, M. T. & Bond, J. S. Structure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers, and high molecular mass multimers. J Biol Chem 278, 2522–2532, doi: 10.1074/jbc.M208808200 (2003).

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of DPYD and the effects of DPYD suppressor luteolin combined with 5‐FU in pancreatic cancer;Cancer Medicine;2024-08

2. A combined ligand-based and structure-based in silico molecular modeling approach to pinpoint the key structural attributes of hydroxamate derivatives as promising meprin β inhibitors;Journal of Biomolecular Structure and Dynamics;2024-01-02

3. Targeting IL-6 trans-signalling: past, present and future prospects;Nature Reviews Immunology;2023-04-17

4. The putative pleiotropic functions of meprin β in gastric cancer;Gastric Cancer;2023-03-28

5. Proteolysis of CD44 at the cell surface controls a downstream protease network;Frontiers in Molecular Biosciences;2023-02-17