Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: Comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex

Author:

Yu Suhong,Yang Xingtian,Zhu Yewei,Xie Fangwei,Lu Yusheng,Yu Ting,Yan Cuicui,Shao Jingwei,Gao Yu,Mo Fan,Cai Guoneng,Sinko Patrick J.,Jia Lee

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference50 articles.

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2. Chen, J. Z. et al. The Unique Pharmacological Characteristics of Mifepristone (RU486): from Terminating Pregnancy to Preventing Cancer Metastasis. Medicinal Research Reviews. 34, 979–1000 (2014).

3. Lalitkumar, S., Bygdeman, M. & Gemzell-Danielsson, K. Mid-trimester induced abortion: a review. Hum Reprod Update. 13, 37–52 (2007).

4. Winikoff, B. Acceptability of medical abortion in early pregnancy. Fam Plann Perspect. 27, 142–148, 185 (1995).

5. Wu, J., Liang, Y., Nawaz, Z. & Hyder, S. M. Complex agonist-like properties of ICI 182,780 (Faslodex) in human breast cancer cells that predominantly express progesterone receptor-B: implications for treatment resistance. Int J Oncol. 27, 1647–1659 (2005).

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